
What We Do
Technology
ADC Technology
Antibody-drug conjugates (ADCs) represent a promising modality for delivering cytotoxic drugs to targeted tumor cells while avoiding off-tumor toxicities.
Despite successes in the past 20 years, development of effective ADCs with broad therapeutic window remains challenging due to the complexity of conjugation technologies and the instability of the linkers.
OBI has developed a suite of proprietary ADC enabling technologies designed to overcome the limitations of conventional ADCs and unlock the full therapeutic potential of antibody-drug conjugates.
These ADC enabling technologies —GlycOBI® and GlycOBI DUO™, EndoSymeOBI®, ThiOBI®, and HYPrOBI™—offer modular and synergistic solutions to enhance conjugation precision, drug loading flexibility, and stability, and leading to improved therapeutic performance.
Together, these ADC enabling technologies provide a robust, comprehensive, and flexible armamentarium of innovative tools to accelerate the development of next-generation ADCs with improved safety, efficacy, and manufacturability.
Platform
Technology Area
Potential Application
Platform
GlycOBI®
Technology Area:
Glycan site-specific conjugation technology
Potential Application:
Cancer treatment
Platform
GlycOBI DUO™
Technology Area:
Site-specific conjugation technology
Potential Application:
Cancer treatment
Platform
ThiOBI®
Technology Area:
Glycan site-specific conjugation technology
Potential Application:
Cancer treatment
Platform
EndoSymeOBI®
Technology Area:
Enzymatic technology
Potential Application:
Cancer treatment
Platform
HYPrOBI™
Technology Area:
Linker technology
Potential Application:
Cancer treatment
Partner with Us
OBI operates with an excellent management team and efficient management model to create an international Taiwan brand, and to base in Taiwan and expand the horizon worldwide.