Careers

• Design and develop modular strategies compatible for rapid access to small molecule targets (strong organic synthesis background is required)
• Learn and employ medicinal chemistry strategies that will enable the discovery of novel, differentiated small molecule and linker candidates for tumor targeted delivery by incorporating optimal structural, pharmacological, physicochemical, metabolic, and safety considerations.
• Prioritize deliverables and projects in fast-paced and dynamic environment.
• Demonstrate creativity, problem-solving and critical thinking skills to overcome challenges all while building/strengthening IP.
• Closely collaborate with project team members and leverage in house resources to meet timelines.
• Regularly attend, present, and actively participate in group meetings as well as write project update reports and participate in writing and submission of patent applications, peer-reviewed articles.
• Stay up to date with literature and patents in synthetic organic chemistry and drug development, advances in medicinal chemistry or ADC field, and advances in broader modalities that influence oncology research.

• Execute animal experiments, including tumor cell expansion, harvest and implantation, monitoring tumor growth, collecting samples (blood, tumor, and organs, etc.) for further analyses.
• Conduct in vitro cell-base assays, such as proliferation, apoptosis, and cytotoxicity.
• Perform molecular biology and biochemistry experiments, such as flow cytometry, RT-PCR analysis, western blot, and ELISA.
• Work with and manage CROs to develop and refine existing protocols and to maintain or enhance support of internal programs.
• Real-time update experimental data to supervisors and team members.
• Routine laboratory notebook writing and progress preparation.
• Support regular laboratory maintenance.
• Perform other items requested by supervisors.