Management Team

Michael Chang

Chief Executive Officer

Dr. Chang is the Chairman and CEO of OBI Pharma, and founder of both Optimer Pharmaceuticals and OBI. Dr. Chang has served as President and Chief Executive Officer at Optimer from November 1998 until May 2010. In 1994, Dr. Chang established Pharmanex, a health products company, which was acquired by NuSkin Enterprises, where he was appointed Chief Scientific Adviser. Prior to this, he founded Cinogen in 1993. Dr. Chang was formerly the Director of Medical Chemistry at Rhone-Poulenc Rorer and Deputy Director of Medicinal Chemistry at Merck, Sharpe & Dohme (US Merck). Dr. Chang received his Ph.D. in Organic Chemistry from Brandeis University, and conducted postdoctoral research at Massachusetts Institute of Technology (MIT). He received his BS in Chemistry from Fu Jen Catholic University in Taiwan. He holds 39 patents and has published more than 69 scientific papers in peer reviewed journals.

Ming-Tain Lai

Chief Scientific Officer

Dr. Lai has more than 23 years of experience in drug discovery. As Senior Principal Scientist at Merck & Co., Dr. Lai led and directed multiple independent project teams to develop potential clinical candidates. He also acted as a core team member of early development and product development in several clinical studies. During his tenure at Merck, the teams have identified more than 10 preclinical candidates. Several of them are currently in clinical trials. He also received several awards from Merck, Merck Divisional/Staff Area Award in 2007, Special achievement award in 2009, and Merck Research Laboratories Pipeline Award in 2018. The crowing achievements of his career at Merck comes with the approval of an antiviral drug by FDA in 2018. Dr. Lai has had over 69 papers published in peer-reviewed journals. Dr. Lai did post-doctoral study in at Massachusetts Institute of Technology, earned his Ph.D. in Bio-Organic Chemistry from University of Minnesota.

Wayne Saville

Chief Medical Officer

Dr. Saville has over thirty years of extensive experience in clinical research, ranging from inpatient care, academic institutions, large pharma, and small biotech. Prior to working with OBI, Dr. Saville held several key leadership roles, including as CMO at Shasqi Inc. from 2020 to 2021, and as VP, Oncology Clinical Development at Xencor Inc. from 2015 to 2020, focusing on bispecific antibody development in oncologic indications. During his tenure at Biogen from 2002 to 2011, Dr. Saville led clinical programs including rituximab (Rituxan), ibritumomab tiuxetan (Zevalin), and natalizumab (Tysabri), as well as several small molecule TKIs.

Dr. Saville received his M.D. from Northwestern University, completed his internal medicine residency at the University of Minnesota, and was a postdoctoral fellow and clinical attending physician at the National Cancer Institute, NIH. He is board-certified in internal medicine and medical oncology.

Frank Chen

Chief Financial Officer

Mr. Chen obtained his master’s degree in Business Administration from National Taiwan University. He currently serves as Vice President, Investment Management Department; Special Assistant to President, Ruentex Group; Chief Financial Officer of OBI Pharma, Inc; the Chairman and CEO of Obigen Pharma, Inc; and is the Director of several companies.

Mitch Che

Chief Operating Officer (USA)

Mitch Che joins OBI Pharma USA Inc. as Chief Operating Officer where he brings over twenty years’ operational and technical expertise spanning the pharmaceutical, telecom, and transportation and logistics industries. Prior to joining OBI Pharma USA Inc., Mitch was Vice President of Facilities, Operations and Procurement for Optimer Pharmaceuticals. Previously, Mitch held positions at AT&T and BP, as well as managing his own executive consulting firm. He is responsible for the development and management of OBI Pharma USA’s operating plans, results, strategic US operations and global IT supporting R&D, clinical and business development plans. Mitch has a B.S. degree in Geochemistry from Brown University and an M.S. degree from the University of California, Berkeley.

Kevin P Poulos

Chief Commercial Officer (USA)

Kevin has over twenty years of senior management experience in various strategic commercial and business development functions  both internationally and the United States with Optimer, Wyeth, Rhone-Poulenc Rorer and SmithKline Beecham. Prior to joining OBI Pharma, Inc., he was the President of KPP Biopharmaceutical Commercial Consulting and the Chief Commercial Officer at Optimer Pharmaceuticals. During his career, Kevin oversaw the international and US commercial launches of many innovative pharmaceutical products including Dificid®, Zyvox®, Synercid®, Zagam®, Zosyn®/Tazocin® and Timentin®. He received his B.S. degree in Business Administration from Old Dominion University.

David Hallinan

Global RA VP (USA)

Dr. Hallinan has over 25 years of operational and regulatory affairs experience across a range of therapeutic areas. Prior to joining OBI, David was VP Regulatory Affairs at Idenix Pharmaceuticals, and VP Regulatory Affairs and Quality Assurance at Parexel International. He holds a Ph.D. in Pharmacology and a B.S. in Biochemistry from University College, Dublin, Ireland.