1.Date of occurrence of the change:2022/11/09
2.Elected or changed position (Please enter institutional director, institutional supervisor, independent director, natural-person director or natural-person supervisor):natural-person director and natural-person supervisor
3.Title and name of the previous position holder:None
4.Resume of the previous position holder:None
5.Title and name of the new position holder:
(1)Director Jeng Her
(2)Supervisor Colin Kao
6.Resume of the new position holder:
(1)Director Jeng Her/ CEO of AP Biosciences.
(2)Supervisor Colin Kao/ Deputy Finance Director, OBI Pharma Inc.
7.Circumstances of change (Please enter “resignation”, “dismissal”, “term expired”, “death” or “new appointment”):new appointment
8.Reason for the change:By-election of director and supervisor
9.Number of shares held by the new position holder when elected:
(1)Director Jeng Her/ 280,000 shares
(2)Supervisor Colin Kao/ 0 shares
10.Original term (from __________ to __________):2021/06/04 ~ 2024/06/03
11.Effective date of the new appointment:2022/11/09
12.Turnover rate of directors of the same term:1/5
13.Turnover rate of independent directors of the same term:N/A
14.Turnover rate of supervisors of the same term:1/2
15.Change in one-third or more of directors (Please enter “Yes” or “No”):No
16.Any other matters that need to be specified:None