1.Date of occurrence of the change:2023/08/07
2.Name of legal person: OBI Pharma, Inc.
3.Name of the previous position holder: Michael Chang
4.Resume of the previous position holder: Former Chairman of the Board, OBI Pharma Inc.
5.Name of the new position holder: Chen-En Tsai
6.Resume of the new position holder: Vice president of Medical Department, OBI Pharma Inc.
7.Reason for the change: Reassignment
8.Original term (from __________ to __________):2021/10/27 to 2024/10/26
9.Effective date of the new appointment:2023/08/07
10.Any other matters that need to be specified: None.