Announcement of resignation of the Chairperson

1.Date of the board of directors resolution or date of occurrence of the change:2023/12/20
2.Position (Please enter chairperson or president/general manager): Chairperson
3.Name of the previous position holder: Yun Yen
4.Resume of the previous position holder: Chairperson of the Board, OBI Pharma Inc.
5.Name of the new position holder: N/A
6.Resume of the new position holder: N/A
7.Circumstances of change (Please enter ”resignation”, ”dismissal”, ”term expired” , ”job relocation”, ”severance”, ”retirement”, ”death” or ”new appointment”):Resignation
8.Reason for the change: Resignation
9.Effective date of the new appointment: N/A
10.Any other matters that need to be specified(the information disclosure also meets the requirements of Article 7, subparagraph 6
of the Securities and Exchange Act Enforcement Rules, which brings forth a significant impact on shareholders rights or the price of
the securities on public companies.):
(1)The Company received the resignation letter of Dr. Yun Yen on 2023/12/20, to resign his position as Chairperson and director of the Company. The
effective date is set on 2023/12/29.
(2)The Company will hold a board meeting to elect the new Chairperson.