Announcement of death of Chairman of the Board (Supplementary Statement on the circumstances of his deputy)

1.Date of the board of directors resolution or date of occurrence of the change: 2022/12/29
2.Position (Please enter chairperson or president/general manager): Chairman of the Board, CEO, and spokesperson
3.Name of the previous position holder: Michael Chang
4.Resume of the previous position holder: Michael Chang/ Chairman of the Board, CEO, and spokesperson, OBI Pharma Inc.
5.Name of the new position holder: Announce after the resolution of Board of Directors
6.Resume of the new position holder: Announce after the resolution of Board of Directors
7.Circumstances of change (Please enter ”resignation”, ”dismissal”, ”term expired” , ”job relocation”, ”severance”, ”retirement”, ”death” or ”new appointment”): death
8.Reason for the change: death
9.Effective date of the new appointment: N/A
10.Any other matters that need to be specified:
(1)The Company’s business is responsible by managers of different levels and has its own deputy rules. The Company’s operation will remain normal.
(2)The duty of Michael Chang, the CEO and spokesperson of the Company, will be represent by his deputy, Ming-Tain Lai, the Chief Scientific Officer. The Company will convene an extraordinary Board of Directors meeting to elect the new Chairman as soon as possible and will make the announcement pursuant to regulations related. (Supplementary Statement)