Announcement of change Spokesperson

1.Type of personnel changed (please enter: spokesperson, acting spokesperson, important personnel (CEO, COO, CMO, CSO, etc.), financial officer, accounting officer, corporate governance
officer, chief information security officer, research and development officer, internal audit officer, or designated and non-designated representatives): Spokesperson
2.Date of occurrence of the change:2023/06/02
3.Name, title, and resume of the previous position holder: Yun Yen / CEO /Chairman of the Board, OBI Pharma Inc.
4.Name, title, and resume of the new position holder: Heidi Wang/ CEO /VP, Oncology Head, Global Regulatory Sciences, Bristol Myers Squibb Company
5.Type of change (please enter: ”resignation”, ”position adjustment”, ”dismissal”, ”retirement”, ”death” or ”new replacement”):new replacement
6.Reason for the change:new replacement
7.Effective date:2023/06/05
8.Any other matters that need to be specified: The Board of Directors appoint Heidi Wang as CEO and Spokesperson today.