Announcement of change of the spokesperson

1.Type of personnel changed (please enter: spokesperson, acting spokesperson, important personnel (CEO, COO, CMO, CSO, etc.), financial officer, accounting officer, corporate governance officer, chief information security officer, research and development officer, internal audit officer, or designated and non-designated representatives): Spokesperson
2.Date of occurrence of the change: 2022/12/30
3.Name, title, and resume of the previous position holder: Michael Chang/ Chairman of the Board and CEO /Chairman of the Board, OBI Pharma Inc.
4.Name, title, and resume of the new position holder: Yun Yen / Chairman of the Board and CEO/ Chairman of the Board, Tanvex BioPharma Inc.
5.Type of change (please enter: ”resignation”, ”position adjustment”, ”dismissal”, ”retirement”, ”death” or ”new replacement”): new replacement
6.Reason for the change: new replacement
7.Effective date: 2022/12/30
8.Any other matters that need to be specified: The former spokesperson, Dr. Michael Chang, passed away on 2022/12/29. The Board of Directors resolved today to appoint Dr. Yun Yen as the new spokesperson.