1.Date of the board of directors resolution or date of occurrence of the change: 2022/12/30
2.Position (Please enter chairperson or president/general manager): CEO
3.Name of the previous position holder: Michael Chang
4.Resume of the previous position holder: Chairman of the Board, OBI Pharma Inc.
5.Name of the new position holder: Yun Yen (represent tentatively)
6.Resume of the new position holder: Chairman of the Board, Tanvex BioPharma Inc.
7.Circumstances of change (Please enter ”resignation”, ”dismissal”, ”term expired” , ”job relocation”, ”severance”, ”retirement”, ”death” or ”new appointment”): new appointment
8.Reason for the change: new appointment
9.Effective date of the new appointment: 2022/12/30
10.Any other matters that need to be specified: The former CEO of the Company, Dr. Michael Chang, passed away on 2022/12/29. The Board of Directors resolved today that the duty of CEO will be represent by Dr. Yun Yen, the Chairman of the Board, tentatively with a term of half year. The Company will seek for adequate candidate continuously.