Announcement of death of Chairman of the Board

1.Date of the board of directors resolution or date of occurrence of the change: 2022/12/29
2.Position (Please enter chairperson or president/general manager): Chairman of the Board and CEO
3.Name of the previous position holder: Michael Chang
4.Resume of the previous position holder: Michael Chang /Chairman of the Board and CEO, OBI Pharma Inc.
5.Name of the new position holder: Announce after the resolution of Board of Directors
6.Resume of the new position holder: Announce after the resolution of Board of Directors
7.Circumstances of change (Please enter ”resignation”, ”dismissal”, ”term expired” , ”job relocation”, ”severance”, ”retirement”, ”death” or ”new appointment”):death
8.Reason for the change: death
9.Effective date of the new appointment: N/A
10.Any other matters that need to be specified: The Company’s business is responsible by managers of different levels and has its own deputy rules. The Company’s operation will remain normal.