1.Date of the board of directors resolution or date of occurrence of the change:2016/06/27
2.Type of personnel (chairman or general manager):Chairman
3.Name and resume of the replaced personnel: Michael Chang, Chairman of OBI Pharma, Inc.
4.Name and resume of the new personnel: Michael Chang, Chairman of OBI Pharma, Inc.
5.Type of the change (please enter: “resignation”, “conge”, “tenure expired” ,“position adjustment”, “dismissal”, “retirement”, “death” or “new appointment” ):tenure expired
6.Reason for the change: tenure expired and the whole Board be elected
7.Effective date of the new appointment:2016/06/27
8.Any other matters that need to be specified: None